Ferric sodium edetate is widely and effectively used in iron supplementation for special populations, primarily due to its excellent chelation capacity and stability. It is a stable chelate compound with no gastrointestinal irritation and specific absorption properties in the duodenum.
In the stomach, it remains tightly bound, and only upon reaching the duodenum is the iron released and absorbed.
Ferric sodium edetate boasts high absorption efficiency and avoids the inhibitory effects of phytates on iron absorption. Research shows that its iron absorption rate is 2 to 3 times higher than that of ferrous sulfate.
Ferric sodium edetate has suitable stability and dissolution properties. After releasing Fe³⁺, the ligand ethylenediaminetetraacetic acid (EDTA) causes no adverse effects or toxicity to the body and is classified as "Generally Recognized as Safe" (GRAS).
Applications of Ferric Sodium Edetate in Iron Supplementation for Special Populations
·Patients with Iron-Deficiency Anemia: Ferric sodium edetate serves as a safe and effective carrier of iron, providing the required iron for the body to prevent and treat iron-deficiency anemia. Its high absorption rate and lack of gastrointestinal irritation make it an ideal iron supplement for these patients.
·Pregnant and Lactating Women: Due to increased physiological demands, pregnant and lactating women are prone to iron deficiency. The high absorption efficiency and safety of ferric sodium edetate make it an ideal choice for iron supplementation during pregnancy and lactation.
·Elderly People: Older adults often experience impaired digestive and absorptive functions, which can lead to poor iron absorption. The duodenal absorption characteristics of ferric sodium edetate make it more effectively absorbed and utilized by elderly individuals, meeting their iron supplementation needs.
·Children: During growth and development, children have a high demand for iron. Ferric sodium edetate, with its high absorption efficiency and lack of a metallic taste, is an ideal choice for iron supplementation in children. It helps promote growth, development, and cognitive advancement in this population.
