The precautions for using ferrous fumarate as a feed additive mainly include the following aspects:
I. Applicability and Cautions
1. Applicability:
·Ferrous fumarate is a safe and efficient organic nutritional iron supplement that promotes hemoglobin synthesis, enhances oxygen-carrying capacity, and maintains high concentrations of hemoglobin and globulin in the blood.
·It improves feed conversion efficiency, promotes animal growth, and reduces feeding costs, thus being widely used in feed additives.
2. Cautions:
·Ferrous fumarate should be used with caution in cases of alcoholism, hepatitis, acute infections, intestinal inflammation (such as diverticulitis, ulcerative colitis, etc.), pancreatitis, and peptic ulceration.
·In these conditions, animals may have reduced tolerance to drugs, or the drug may exacerbate the underlying condition.
II. Dosage and Monitoring
1. Dosage:
·The appropriate dosage of ferrous fumarate should be determined based on the animal species, age, weight, and feeding purpose.
·Generally, it should be used strictly according to the product instructions or veterinary advice.
2. Monitoring Indicators:
·Before, during, and after using ferrous fumarate, regular monitoring of animals' hemoglobin, reticulocyte count, serum ferritin, and serum iron levels should be conducted.
·These indicators reflect the metabolic status of iron and the synthesis of hemoglobin in animals.
III. Drug Interactions and Contraindications
1. Drug Interactions:
·Taking ferrous fumarate with vitamin C can increase iron absorption but may also lead to gastrointestinal reactions.
·Concurrent use with drugs such as cimetidine, deferoxamine, dimercaprol, and pancreatin may affect iron absorption.
·When used with antacids (such as sodium bicarbonate, phosphates, and tannin-containing drugs), precipitation may occur, affecting absorption.
2. Contraindications:
·Ferrous fumarate should be avoided in combination with the aforementioned drugs that affect iron absorption.
·Care should be taken to avoid mixing ferrous fumarate with other substances that may produce precipitation or affect absorption.
IV. Other Precautions
1. Storage Conditions:
·Ferrous fumarate should be stored in a dry, cool, well-ventilated place, away from direct sunlight and high temperatures.
·The packaging should remain intact during storage to prevent moisture and contamination.
2. Expiry Date:
·Pay attention to the production date and validity period of the product to avoid using expired products.
3. Individual Differences:
·Different animals may exhibit varying tolerances and responses to ferrous fumarate.
·Close observation of animals' reactions during use is necessary, and veterinary advice should be sought promptly if adverse reactions occur.
4. Hazards of Overdose:
·Excessive ferrous fumarate can lead to acute poisoning, particularly dangerous for children.
·Ingesting a large amount of iron at once can cause severe gastrointestinal reactions, liver and kidney damage, or even death.
·Therefore, strict control of dosage is crucial to avoid overdose when using ferrous fumarate.
In summary, the use of ferrous fumarate as a feed additive requires attention to applicability, dosage and monitoring, drug interactions and contraindications, and other related matters. During use, relevant regulations and recommendations should be strictly adhered to ensure the safety and health of animals.
